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United States Military HIV Research Program
The United States Military HIV Research Program (USMHRP or MHRP) is a program initiated by the United States Congress in 1986. It is centered at the Walter Reed Army Institute of Research (WRAIR), and has established five international research sites in Africa and Asia (Tanzania, Kenya, Nigeria, Uganda and Thailand). Its primary focus is developing a globally effective HIV-1 vaccine,〔 〕 but the program also provides prevention, care, and treatment through the President's Emergency Plan for AIDS Relief (PEPFAR).
==International vaccine research==
One of the program's largest projects was the RV 144 vaccine study of 16,000 volunteers in Thailand. In September 2009, trial collaborators announced positive results indicating that the vaccine was safe and reduced the risk of HIV infection by approximately 31%.〔(【引用サイトリンク】title=In Thailand Clinical Study, HIV Vaccine Regimen Demonstrates Modest Preventive Effect )〕〔(【引用サイトリンク】title=HIV vax testers react to Thai trial )〕〔(【引用サイトリンク】 title=HIV Vaccine Study First to Show Some Effectiveness in Preventing HIV ) Also see (Frequently asked questions regarding the RV144 Phase III HIV Vaccine Trial ) and (Thailand MHRP site information ).〕 Although the efficacy is modest, this study represents a major scientific achievement that has important implications for HIV vaccine testing and development. MHRP provided study leadership and is working with researchers around the globe to dissect the results from the RV144 trial and to design future clinical trials to translate a scientific milestone into an eventual public health tool. MHRP scientists are also pursuing other global vaccine strategies, which include MVA vaccines developed by MHRP and NIAID researchers.
In addition to vaccine development and testing, MHRP also conducts therapeutic research, tracks the HIV epidemic in active-duty forces, assesses the risk of HIV exposure to deployed U.S. and allied forces overseas, and conducts all HIV-1 testing for the Army.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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